782493-42-9

Basic information

• Product Name: tert-Butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate
• Synonyms: tert-Butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate;tert-butyl 4-(3-oxo-2,3-dihydroisoxazol-5-yl)piperidine-1-carboxylate;4-(2,3-Dihydro-3-oxo-5-isoxazolyl)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester
• CAS NO: 782493-42-9
• Molecular Formula: C₁₃H₂₀N₂O₄
• Molecular Weight: 268.3089
• Mol File: 782493-42-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-Butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate(782493-42-9)
• EPA Substance Registry System: tert-Butyl 4-(3-hydroxyisoxazol-5-yl)piperidine-1-carboxylate(782493-42-9)

Safety Data

• Hazardous Substances Data: 782493-42-9(Hazardous Substances Data)

Usage

Uses

4-(2,3-Dihydro-3-oxo-5-isoxazolyl)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is a compound used in the preparation of anti-inflammatory agents as well as derivatives for regulators of immunoregulatory diseases.

Upstream product

• 203663-59-6 tert-butyl 4-(3-ethoxy-3-oxoprop-1-yn-1-yl)piperidine-1-carboxylate 
• 203664-61-3 4-(2,2-dibromo-vinyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 782493-41-8 5-(piperidin-4-yl)isoxazol-3-ol hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 782493-43-0 tert-butyl 4-(3-{[(4-methylphenyl)sulfonyl]oxy}isoxazol-5-yl)piperidine-1-carboxylate 

Relevant articles and documents

NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST

The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

BENZOXAZINYL-AMIDOCYCLOPENTYL-HETEROCYCLIC MODULATORS OF CHEMOKINE RECEPTORS

Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I: which are used to modulate the CCR-2 chemokine receptor to prevent or treat inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions.