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78281-02-4

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78281-02-4 Usage

Biological Activity

Hydroxysafflor yellow A is a pigment that has been found in C. tinctorius and has diverse biological activities. It inhibits LPS-induced increases in NF-κB levels and production of nitric oxide (NO), IL-1β, and TNF-α in primary mouse embryonic mesencephalic cultures when used at concentrations of 40 and 160 μM.

in vivo

Hydroxysafflor yellow A (1 and 3 mg/kg) decreases mean arterial pressure (MAP) and heart rate in anesthetized normotensive or spontaneously hypertensive rats. It reduces infarct volume and serum superoxide dismutase (SOD) activity in a rat model of focal transient cerebral is chemia induced by middle cerebral artery occlusion (MCAO) when administered at doses of 2, 4, and 8 mg/kg.

Check Digit Verification of cas no

The CAS Registry Mumber 78281-02-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,2,8 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 78281-02:
(7*7)+(6*8)+(5*2)+(4*8)+(3*1)+(2*0)+(1*2)=144
144 % 10 = 4
So 78281-02-4 is a valid CAS Registry Number.
InChI:InChI=1/C27H32O16/c28-7-11-16(32)25(43-26(40)17(11)33)27(41)23(38)14(12(31)6-3-9-1-4-10(30)5-2-9)19(35)15(24(27)39)22-21(37)20(36)18(34)13(8-29)42-22/h1-6,11,13,16-18,20-22,25-26,28-30,32-34,36-41H,7-8H2/b6-3+/t11-,13-,16-,17+,18-,20+,21-,22+,25+,26+,27?/m1/s1

78281-02-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Hydroxysafflor yellow A

1.2 Other means of identification

Product number -
Other names hydroxysaffloryellowA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78281-02-4 SDS

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