78347-93-0Relevant academic research and scientific papers
LITHIATION OF SOME 3THIOPHENES AND INTRAMOLECULAR TRANSMETALATION
Gronowitz, Salo,Stenhammar, Karin,Svensson, Leif
, p. 947 - 959 (2007/10/02)
The reaction of some halo-1-(thienyl)-2-phenylethanes such as 3-(2-phenylethyl)thiophene (1), 3-thiophene (2), 4--2-methylthiophene (3) and 4--2-chlorothiophene (4) with butyllithium and lithium diisopropylamide (LDA) under various conditions has been investigated.Competition between halogen-metal exchange in the benzene ring and metalation of thiophene ring was observed and an intramolecular transmetalation reaction was found.
