78364-64-4Relevant academic research and scientific papers
Discovery of 3,3a,4,5-tetrahydro-2H-benzo[g]indazole containing quinoxaline derivatives as novel EGFR/HER-2 dual inhibitors
Zong, Xi,Cai, Jin,Chen, Junqing,Sun, Chunlong,Li, Lushen,Ji, Min
, p. 24814 - 24823 (2015)
In the present study, twenty-five pyrazole-quinoxaline derivatives (4a-4y) were designed and synthesized, and their biological activity as potential EGFR or HER-2 kinase inhibitors was evaluated. Among them, compound 4l displayed better antiproliferative
Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents
Agarwal,Sharma, Vidisha,Shakya, Nishi,Gupta, Suman
scheme or table, p. 5474 - 5477 (2010/08/19)
4-(Substituted-benzylidine)-2-substituted-5,6-dihydrobenzo[h]quinazoline (5a-p) and 4-(substituted-benzylidine)-2-substituted-3, 4, 5, 6-tetrahydrobenzo[h]quinazoline (6a-p) have been synthesized from 2-(substituted-benzylidine)tetralone-1(3a-d) and sever
Fused Heterocycles: Part III - Attempted Synthesis of 4,5-Dihydro-3-arylnaphthisoxazoles
Rao, C. Janakiram,Reddy, K. Malla,Murthy, A. Krishna
, p. 282 - 284 (2007/10/02)
2-Benzal-1-tetralone dibromide (II), obtained by the bromination of 2-benzal-1-tetralone, on treatment with hydroxylamine hydrochloride in the presence of alc.KOH undergoes cyclization to the unexpected product 3,3a,4,5-tetrahydro-3-arylnaphthisoxa
