78374-90-0Relevant academic research and scientific papers
A New, Convenient Synthesis of 1,6-Diaryl-2-thioxoperhydro-4-pyrimidinones: Reaction of 3-Phenyl-2-propenoyl Isothiocyanate With Aromatic and Heteroaromatic Amines
Hafez, Ebtisam Abdal Aziz,Elmoghayar, Mohamed Rifaat Hamza,Ramiz, Mahmoud Mohamed Mahfouz
, p. 65 - 68 (2007/10/02)
The substituted thioureas 3a-h, prepared from 3-phenyl-2-propenoyl isothiocyanate (1) and aromatic or heteroaromatic amines 2a-h, cyclize in the presence of sodium ethoxide to give the perhydropyrimidine derivatives 5a-c.
A Novel Synthesis of Perhydrpyrimidine-2-thiones
Gohar, Abdel-Kerim M. N.,Abdel-Latif, F. F.,Regaila, H. A. A.
, p. 767 - 768 (2007/10/02)
Cinnamoyl isothiocyanate (1) reacts with amines (aniline, p-toluidine, benzylamine) to give the corresponding cinnamoylthiourea derivatives (2a-c).Compounds 2a-c undergo cyclization when refluxed with sodium ethoxide solution to give the corresponding per
