78401-46-4

Basic information

• Product Name: 2,2-dichloro-1-(4-methoxyphenyl)-pent-4-en-1-one
• CAS NO: 78401-46-4
• Molecular Weight: 259.132
• Mol File: 78401-46-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2-dichloro-1-(4-methoxyphenyl)-pent-4-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dichloro-1-(4-methoxyphenyl)-pent-4-en-1-one(78401-46-4)
• EPA Substance Registry System: 2,2-dichloro-1-(4-methoxyphenyl)-pent-4-en-1-one(78401-46-4)

Safety Data

• Hazardous Substances Data: 78401-46-4(Hazardous Substances Data)

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 138983-08-1 Dichlor<(1,1-dimethylethyl)dimethylsilyl>methan 
• 106-95-6 allyl bromide 
• 78401-33-9 1-(1-Allyloxy-2,2,2-trichloro-ethyl)-4-methoxy-benzene 
• 14337-31-6 2,2,2-trichloro-1-(4-methoxyphenyl)ethan-1-ol 
• 78401-59-9 1-(1-Allyloxy-2,2-dichloro-vinyl)-4-methoxy-benzene 

Relevant articles and documents

Reaction of silyldihalomethyllithiums with nitriles: Formation of α-keto acylsilanes via azirines and 1,3-rearrangement of silyl group from C to N

A synthesis of α-keto acylsilanes, where 2-bromo-2H-azirine participates as a key intermediate, is reported. The reaction of silyldibromomethyllithium with aryl nitriles provides α-keto acylsilanes in good yields. Interestingly, silyldichloromethyllithium induces aza-1,3-Brook rearrangement of the silyl group in th reaction with nitriles. The rearrangement enables a three-component coupling reaction in a one-pot operation. Copyright