784093-32-9 Usage
Uses
Used in Pharmaceutical Industry:
3-Phenylbicyclo[1.1.1]pentan-1-amine is used as a synthetic intermediate for the preparation of triazolopyridines. These triazolopyridines are of significant interest due to their potential as inhibitors of myeloperoxidase and/or eosinophil peroxidase. Myeloperoxidase and eosinophil peroxidase are enzymes involved in the immune response, and their inhibition can help in the treatment of various inflammatory and immune-related disorders.
In the synthetic preparation of triazolopyridines, 3-phenylbicyclo[1.1.1]pentan-1-amine serves as a key building block, providing the necessary structural features for the formation of the desired triazolopyridine scaffold. The synthesis of these bioactive molecules often involves multi-step reactions, with 3-phenylbicyclo[1.1.1]pentan-1-amine playing a crucial role in the construction of the final product.
Overall, 3-phenylbicyclo[1.1.1]pentan-1-amine is a valuable compound in the field of medicinal chemistry, particularly for the development of novel therapeutic agents targeting myeloperoxidase and eosinophil peroxidase. Its unique structural features and synthetic utility make it an important component in the design and synthesis of innovative pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 784093-32-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,4,0,9 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 784093-32:
(8*7)+(7*8)+(6*4)+(5*0)+(4*9)+(3*3)+(2*3)+(1*2)=189
189 % 10 = 9
So 784093-32-9 is a valid CAS Registry Number.
784093-32-9Relevant academic research and scientific papers
Adcock, William,Baran, Yakup,Filippi, Antonello,Speranza, Maurizio,Trout, Neil A.
, p. 1029 - 1034 (2005)
(Chemical Equation Presented) Experimental gas-phase acidities are reported for a series of 3-substituted (X) bicyclo [1.1.1]pent-1-yl carboxylic acids (1, Y = COOH). A comparison with available calculated data (MP2/6-311++G* *// B3LYP/6-311+G**) reveals
COMPOUNDS FOR THE TREATMENT OF PAIN
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, (2019/08/20)
Provided herein are compounds that are useful in the treatment of pain in a subject.
