784123-63-3Relevant academic research and scientific papers
Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676
Wolner, Ilse,Kassack, Matthias U.,Ullmann, Heiko,Karel, Anton,Hohenegger, Martin
, p. 525 - 533 (2005)
1. The skeletal muscle Ca2+ release channel, the ryanodine receptor, is activated by the trypanocidal drug suramin via the calmodulin-binding site. As calmodulin activates and inhibits the ryanodine receptor depending on whether Ca2+
