78415-89-1 Usage
Uses
Used in Organic Synthesis:
Cyclobutane, (chloromethyl)is utilized as a key intermediate in organic synthesis for the production of various organic compounds. Its unique structure and reactivity allow for the formation of new chemical bonds and the synthesis of complex molecules, making it a valuable component in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Cyclobutane, (chloromethyl)serves as a building block for the development of new drugs. Its structural properties and reactivity enable the design and synthesis of novel drug candidates with potential therapeutic applications. Researchers can exploit its chemical properties to create molecules with specific biological activities, contributing to the advancement of medicinal chemistry.
Used in Chemical Research:
Cyclobutane, (chloromethyl)is also employed in chemical research to study the properties and reactions of halogenated alkyl groups. Understanding its reactivity and interaction with other chemical species can provide insights into the development of new reaction mechanisms and the discovery of innovative synthetic routes for the preparation of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 78415-89-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,1 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 78415-89:
(7*7)+(6*8)+(5*4)+(4*1)+(3*5)+(2*8)+(1*9)=161
161 % 10 = 1
So 78415-89-1 is a valid CAS Registry Number.
78415-89-1Relevant academic research and scientific papers
The Kinetics and Mechanism of Ring Opening of Radicals containing the Cyclobutylcarbinyl System
Beckwith, Athelstan L. J.,Moad, Graeme
, p. 1083 - 1092 (2007/10/02)
The kinetic parameters of β-fission of radicals containing the cyclobutylcarbinyl system have been determined by analysis of the mixtures obtained when suitable chloro-compounds are treated with tributylstannane.Under these conditions ring opening is irreversible and in the rigid bicyclic system (4) is under stereoelectronic control.For ring opening of cyclobutylcarbinyl radical (8) kf = 4.3 x 103 s-1 at 60 deg C, and the best values of the activation parameters appear to be ΔH(excit.) = 12.2 kcal mol-1 and ΔS(excit.) = -7.4 cal mol-1 K-1.Monocyclic systems undergo preferential fission of the more substituted βγ-bond.Methyl substituents at the α-, β-, or δ-positions have little effect but γ-substitution strongly enhances the rate of ring opening.The transition state is reactant-like and has a similar disposition of centres to that (1) for homolytic addition.
