78416-81-6 Usage
Uses
Trequinsin Hydrochloride is an ultrapotent inhibitor of phosphodiesterase (PDE) 3.
Biological Activity
Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.
Check Digit Verification of cas no
The CAS Registry Mumber 78416-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,1 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 78416-81:
(7*7)+(6*8)+(5*4)+(4*1)+(3*6)+(2*8)+(1*1)=156
156 % 10 = 6
So 78416-81-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H27N3O3.ClH/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4;/h9-13H,7-8H2,1-6H3;1H/b25-22-;
78416-81-6Relevant articles and documents
Use of pyrimido-(6,1-a)-isoquinolin-4-one derivatives and medicinal preparations based on these compounds
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, (2008/06/13)
Pyrimido-(6,1-a)-isoquinolin-4-one derivatives of the formula STR1 in which the substituents R1 -R6 have the meanings mentioned, are suitable for the prevention of hair loss and for strengthening hair growth.