784191-96-4

Upstream product

• 934768-45-3 tert-butyl N-[1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(phenylsulfonyl)methyl]carbamate 
• 784191-95-3 (1S)-1(R)-[(tert-butoxycarbonyl)amino]-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-2-propenyl acetate 
• 1053255-62-1 [(1S,2S)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-but-3-enyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

An efficient diastereoselective route to differentially protected anti-4-amino-1-alken-3-ols

Zinc-promoted hydroxyallylation of α-amidoalkyl arylsulfones 4 using 3-bromo-propenyl methyl carbonate 5 proceeds smoothly in DMF at room temperature to afford high yields of differentially protected anti-1,2-amino alcohols 6.

Reactivity of chiral α-amidoalkylphenyl sulfones with stabilized carbanions. Stereoselective synthesis of optically active 1-aminopyrrolizidine

Metal enolates and functionalized allylzinc reagents react with optically active α-amidoalkylphenyl sulfones to give N-carbamoylamino derivatives with variable levels of anti diastereoselectivity. Zinc enolates provide comparable results with respect to l