78426-08-1Relevant academic research and scientific papers
Synthesis and characterization of 2-benzylidene-1,3-indandione derivatives as in vitro quantification of amyloid fibrils
Adibi, Hadi,Mehrabi, Maryam,Amiri, Kazhal,Balalaie, Saeed,Khodarahmi, Reza
, p. 423 - 432 (2020)
Timely detection of amyloid aggregations has a critical role in the treatment of degenerative nervous system disorders such as Alzheimer’s, Parkinson’s disease and systemic amyloidosis. Thioflavin T (ThT) is a dye considered for the detection of amyloids.
In vitro anti-melanogenic effects of chimeric compounds, 2-(substituted benzylidene)-1,3-indanedione derivatives with a β-phenyl-α, β -unsaturated dicarbonyl scaffold
Ryu, Il Young,Choi, Inkyu,Jung, Hee Jin,Ullah, Sultan,Choi, Heejeong,Al-Amin, Md.,Chun, Pusoon,Moon, Hyung Ryong
, (2021/02/16)
Tyrosinase is considered a key contributor to melanogenesis, and safe, potent tyrosinase inhibitors are needed for medical and cosmetic purposes to treat skin hyperpigmentation and prevent fruit and vegetable browning. According to our accumulated SAR dat
