78427-15-3Relevant academic research and scientific papers
KINETIC AND SPECTRAL STUDIES ON 5-PHENOXY-2-FURALDEHYDES AND THEIR CONDENSATION PRODUCTS
Knoppova, Viera,Dandarova, Miloslava,Kovac, Jaroslav
, p. 506 - 514 (2007/10/02)
The base-catalysed reaction of 5-(4- or 3-phenoxy)-2-furaldehydes (X = 4-OCH3, 4-CH3, 4-Cl, 4-NO2, 3-NO2, 4-Br, 4-COOC2H5, 3-NHCOCH3, 4-SCH3) with malonodinitrile in ethanol gave the corresponding condensation products.The course of the reaction has been monitored kinetically.The kinetics of the nucleophilic substitution reaction at the position 5 of the furan ring of the obtained 2-cyano-3-(5-X-phenoxy-2-furyl)acrylonitriles with secondary cyclic amines (piperidine, morpholine, pyrrolidine) has been studied.The effect of X across the oxygen bridge upon the reactionsite is discussed from the point of view of kinetics of the reaction. 1H-NMR spectra of the starting aldehydes and of the formed condensation products have been measured.
