78440-51-4

Upstream product

• 78440-65-0 6-chloro-3-(phenylthio)-2H-1-benzopyran-2-one 
• 7605-30-3 ethyl 2-phenylsulfonylacetate 
• 635-93-8 5-chlorosalicyclaldehyde 
• 7605-28-9 2-(phenylsulfonyl)acetonitrile 
• 832147-58-7 C₁₅H₁₀ClNO₃S 

Relevant academic research and scientific papers

An ecofriendly approach to the synthesis of 2-imino- and 2-oxo-3-phenylsulfonyl-2H-chromenes

An efficient synthesis for 2-imino-3-phenylsulfonyl-2H-chromenes was developed from the Knoevenagel condensation of (phenylsulfonyl)acetonitrile and salicylaldehydes in aqueous sodium carbonate solution, at room temperature. Hydrolysis in aqueous HCl, at

Samarium (III) triiodide catalysed reaction of salicylaldehydes with active methylene compounds

The unambiguous synthesis and isolation of 2-oxo-2H-1-benzopyran derivatives are described. The Knoevenagel condensation of 2-hydroxy benzaldehydes with active methylene compounds catalysed by samarium triiodide resulted in coumarium derivatives in fair yields under refluxing conditions.

Synthesis of 3-Coumaryl Phenyl Sulfones or Sulfoxides

An unambiguous synthesis of a number of 3-coumaryl phenyl sulfones or sulfoxides have been described which were obtained by the oxidation of the corresponding sulfides with hydrogen peroxide.The sulfides were prepared by the Perkin-Oglialore reaction of o-hydroxyaldehyde with the sodium salt of different S-phenyl thioacetic acids.The sulfones did not exhibit any appreciable antituberculous activity in the preliminary screening tests.