78440-57-0Relevant academic research and scientific papers
Stereospecificity of diels-Alder reactions validated using Ab initio calculations: Synthesis of novel coumarin and phenanthridine derivatives
El-Shafei,Fadda,Abdel-Gawad,Youssif
experimental part, p. 2954 - 2972 (2009/12/03)
A new series of coumarin derivatives (2-5) was synthesized by reaction of phenylsulfonylacetonitrile (1) with 2-hydroxy-1-naphthaldehyde and/or salicyaldehyde. Compounds 3 and 5 were converted to the corresponding phenanthridine analogs 6 and 7, respectiv
Utility of sulphones in heterocyclic synthesis: Synthesis of some pyridine, chromene and thiophene derivatives
Fadda,Refat, Hala M.,Zaki
, p. 701 - 709 (2007/10/03)
Phenylsulfonylacetonitrile (1) when reacted with α,β-unsaturated nitriles (2a,b) and/or 2-hydroxynaphthaldehyde yields pyridine derivatives (3a,b) and / or the imino-chromene derivative (4) respectively. The behavior of (1) towards some α-halogenated compounds has been investigated.
Synthesis of 3-Coumaryl Phenyl Sulfones or Sulfoxides
Merchant, J.R.,,Shah, P.J.,
, p. 441 - 442 (2007/10/02)
An unambiguous synthesis of a number of 3-coumaryl phenyl sulfones or sulfoxides have been described which were obtained by the oxidation of the corresponding sulfides with hydrogen peroxide.The sulfides were prepared by the Perkin-Oglialore reaction of o-hydroxyaldehyde with the sodium salt of different S-phenyl thioacetic acids.The sulfones did not exhibit any appreciable antituberculous activity in the preliminary screening tests.
