78449-78-2

Basic information

• Product Name: 2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine(SALTDATA: FREE)
• Synonyms: Tetrahydro-1H-Pyrrolizine-7a(5H)-ethanamine;2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine(SALTDATA: FREE)
• CAS NO: 78449-78-2
• Molecular Formula: C₉H₁₈N₂
• Molecular Weight: 154.26
• Mol File: 78449-78-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 197.098 °C at 760 mmHg
• Flash Point: 70.378 °C
• Appearance: /
• Density: 1.023 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine(SALTDATA: FREE)(78449-78-2)
• EPA Substance Registry System: 2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine(SALTDATA: FREE)(78449-78-2)

Safety Data

• Hazardous Substances Data: 78449-78-2(Hazardous Substances Data)

Usage

General Description

2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)ethanamine is a chemical compound that has been identified as a salt form with the name "SALTDATA: FREE." It is an amine derivative, containing a tetrahydropyrrolizine ring structure. Amines are organic compounds that contain a basic nitrogen atom. This particular compound has a unique structure that may have application in pharmaceuticals or other chemical processes. Further research and exploration of its properties and potential uses are necessary to fully understand its potential.

Upstream product

• 78449-75-9 (1-azabicyclo<3.3.0>octan-5-yl)acetonitrile 
• 40624-07-5 1,7-dichloro-4-heptanone 
• 20463-30-3 Δ¹⁽⁸⁾-dehydropyrrolizidine 
• 107825-25-2 (E)-4,4’,5,5’-tetrahydro-2’H,3H-[2,3’-bifuranylidene]-2’-one 

Downstream Products

• 167889-09-0 2-<2-(1-azabicyclo<3.3.0>octan-5-yl)ethylamino>benzonitrile 
• 236111-70-9 5-(2-benzyloxycarbonylaminoethyl)-1-azabicyclo<3.3.0>octane 
• 905557-28-0 N-[4-[[2-(hexahydro-1H-pyrrolizin-7a-yl)ethylamino]methyl]-3-hydroxyphenyl]acetamide 
• 236111-76-5 N-<2-(1-azabicyclo<3.3.0>octan-2-one-5-yl)ethyl>-4-(4-methoxybenzyloxy)-2-nitroaniline 
• 236111-77-6 N-<2-(1-azabicyclo<3.3.0>octan-2-on-5-yl)ethyl>-4-hydroxy-2-nitroaniline 
• 236111-71-0 5-(2-benzyloxycarbonylaminoethyl)-1-azabicyclo<3.3.0>octan-2-one 

Relevant articles and documents

Pyrrolizidines for direct air capture and CO2 conversion

Greenhouse gases such as CO2 strongly contribute to the rising temperatures of our planet, but as long as our society is dependent on fossil fuels, this trend will even increase in the near future. Therefore, CO2 capture and subseque

Synthesis and muscarinic activity of a series of quinolines and naphthalenes with a 1-azabicyclo[3.3.0]octane moiety

In order to discover a medicine effective against Alzheimer's disease, we synthesized a series of quinoline derivatives having a characteristic 1- azabicyclo[3.3.0]octane amine ring, and performed pharmacological evaluation of them. Acetylcholine esterase inhibitory activities of these derivatives were unexpectedly weak. Tests for central nervous muscarinic cholinergic receptor binding affinity indicated that these compounds had higher affinities to muscarinic M1 receptors than to M2 receptors. A series of naphthalene derivatives substituted with the 1-azabicyclo[3.3.0]octane ring were also synthesized and muscarinic M1 and M2 receptor binding affinity determined. These compounds had much higher affinity for M1 receptors than the quinoline derivatives, and 1-[N-(1-azabicyclo[3.3.0]octan-5-yl)methyl-N- methylamino]-4-nitronaphthalene showed the highest affinity and selectivity. The ability of this compound to improve cognitive function was assessed using the passive avoidance test in scopolamine-induced mice.

Application of 1,2,3,5,6,7-hexahydropyrrolizinium perchlorate in the synthesis of 7a-substituted hexahydro-1H-pyrrolizines [1]

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