78456-82-3

Upstream product

• 73670-94-7 2-(2,5-Dihydro-1,1-dioxothienyl)acetyl chloride 
• 78456-78-7 (E)-N-(p-methoxybenzyl)-N-<<3,4-(methylenedioxy)benzylidene>methyl>-2-(2,5-dihydro-1,1-dioxothienyl)acetamide 
• 6543-34-6 benzo[1,3]dioxol-5-yl-acetaldehyde 
• 2393-23-9 4-methoxy-benzylamine 
• 78456-80-1 N-(p-methoxybenzyl)-2-oxo-7-<3,4-(methylenedioxy)phenyl>-2,3,3a,6,7,7a,-hexahydroindole 
• 78456-86-7 [2-Benzo[1,3]dioxol-5-yl-eth-(Z)-ylidene]-(4-methoxy-benzyl)-amine 

Downstream Products

• 78456-84-5 (3aR*,7S*,7aS*)-N-carbethoxy-7-<3,4-(methylenedioxy)phenyl>-2,3,3a,6,7,7 
• 78456-85-6 [(1S,2R,6R)-6-Benzo[1,3]dioxol-5-yl-2-(2-chloro-ethyl)-cyclohex-3-enyl]-(4-methoxy-benzyl)-carbamic acid ethyl ester 
• 78456-84-5 (3aR,7R,7aS)-7-Benzo[1,3]dioxol-5-yl-2,3,3a,6,7,7a-hexahydro-indole-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Intramolecular Cycloadditions as a General Strategy for Alkaloid Synthesis. A Novel Formal Synthesis of Lycorine

The intramolecular cycloadditions of the aryl-substituted enamido dienes that were produced upon thermal, cheletropic extrusion of sulfur dioxide from the enamides 8,15, and 26 were examined.Whereas thermolysis of 8 in refluxing xylene in the pres

General Strategies for Alkaloid Synthesis via Intramolecular Cycloadditions of Enamides. Application to the Formal Total Synthesis of Racemic Lycorine.

The application of the intramolecular cycloaddition of the enamido diene 6 to the construction of the unsaturated oxolycorane 2 is described, thereby completing a novel, formal synthesis of the Amaryllidaceae alkaloid lycorine (1).