78460-76-1

Basic information

• Product Name: 2-(2-amino-4-methylphenoxy)-5-nitrobenzoic acid
• CAS NO: 78460-76-1
• Molecular Weight: 288.26
• Mol File: 78460-76-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-amino-4-methylphenoxy)-5-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-amino-4-methylphenoxy)-5-nitrobenzoic acid(78460-76-1)
• EPA Substance Registry System: 2-(2-amino-4-methylphenoxy)-5-nitrobenzoic acid(78460-76-1)

Safety Data

• Hazardous Substances Data: 78460-76-1(Hazardous Substances Data)

Upstream product

• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 95-84-1 3-amino-4-hydroxytoluene 

Downstream Products

• 78460-68-1 5-nitro-N-(5-methyl-2-hydroxyphenyl)anthranilic acid 

Relevant articles and documents

Synthesis of 5H-Benzoxazoloquinazolin-5-ones

5H-Benzoxazoloquinazolin-5-ones (Xa-d) were synthesized in excellent yields from N-(2-hydroxyphenyl)anthranilic acids (Ia-d) and cyanogen bromide.The synthesis was based on the mechanistic consideration of the reactions of salicylic acid with cyanogen bromide previously reported in the literature.A versatile alternative route to these novel heterocyclic compounds was through thermal cyclization of N-(2-benzoxazolyl)-2-fluorobenzamides (XIII) obtained by reacting 2-fluorobenzoyl chloride with 2-aminobenzoxazoles.The reaction of Xb with ethanol in the presence of potassium hydroxide gave an ethoxyquinazolinone (XVII).Similarly, the alkaline hydrolysis of Xb afforded an quinazolindione (XVIII).