78465-00-6Relevant academic research and scientific papers
ANOMALOUS REACTIVITY OF METHYLIDENEMALONATES IN THE PRILEZHAEV REACTION. EVIDENCE FOR A 1,3-DIPOLAR MECHANISM.
Cock, Christian J. C. De,Keyser, Jean-Luc De,Poupaert, Jacques H.,Dumont, Pierre
, p. 783 - 786 (2007/10/02)
Methylidenemalonates are converted into the corresponding oxiranes in 81-97 percent yield when treated with m-chloroperbenzoic acid in solution in refluxing dichloromethane (Prilezhaev reaction).Results suggest that Prilezhaev's epoxidation of methylidenemalonates proceed via 1,3-dipolar addition process in sharp contrast with the behaviour of acrylates.
Stoffwechselproducte von Mikroorganismen. Strukturaufklaerung von Elaiophylin: Spektroskopische Untersuchungen und Abbau
Kaiser, Hanspeter,Keller-Schierlein, Walter
, p. 407 - 424 (2007/10/02)
The structure of the antibiotic elaiophylin (azalomycin B) was elucidated by extended spectroscopic investigations and chemical degradation.Elaiophylin (26) is a macrodiolide with a 16 membered dilactone ring.The synthesis of 7-acetoxy-6-ethyl-3-octanone (14), the acetyl derivative of an important degradation product, is described.
