78478-28-1

Basic information

• Product Name: PRAERUPTORIN E
• Synonyms: (9S)-2-Oxo-8,8-dimethyl-9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-9β,10β-diol 9-[(Z)-2-methyl-2-butenoate] 10-(3-methylbutanoate);(Z)-2-Methyl-2-butenoic acid [(9S,10S)-9,10-dihydro-8,8-dimethyl-10-(3-methyl-1-oxobutoxy)-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran]-9-yl ester;9,10-Dihydro-2-oxo-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-9β,10β-diol 9-[(Z)-2-methyl-2-butenoate] 10-isovalerate;Pd-III;Praeruptorin E
• CAS NO: 78478-28-1
• Molecular Formula: C24H28O7
• Molecular Weight: 428.47492
• Mol File: 78478-28-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 516.5 °C at 760 mmHg
• Flash Point: 221.4 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 8.92E-11mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: PRAERUPTORIN E(CAS DataBase Reference)
• NIST Chemistry Reference: PRAERUPTORIN E(78478-28-1)
• EPA Substance Registry System: PRAERUPTORIN E(78478-28-1)

Safety Data

• Hazardous Substances Data: 78478-28-1(Hazardous Substances Data)

Usage

General Description

Praeruptorin E is a bioactive compound found in the medicinal herb Peucedanum praeruptorum. It is a prenylated coumarin with various pharmacological activities, including anti-inflammatory, anti-cancer, and anti-osteoporosis properties. Praeruptorin E has been studied for its potential to inhibit the growth of cancer cells and induce apoptosis, as well as its ability to suppress the production of inflammatory molecules. Additionally, it has been shown to have protective effects on bone health by inhibiting osteoclast formation and bone resorption. Overall, Praeruptorin E shows promise as a natural compound with diverse therapeutic potential.

InChI:InChI=1/C24H28O7/c1-7-14(4)23(27)30-22-21(29-18(26)12-13(2)3)19-16(31-24(22,5)6)10-8-15-9-11-17(25)28-20(15)19/h7-11,13,21-22H,12H2,1-6H3/b14-7-/t21-,22-/m0/s1

Downstream Products

• 518-76-3 (+)-(3'S,4'R)-trans-khellactone 
• 54712-23-1 (-)-cis-(3'S,4'S)-khellactone