78493-48-8Relevant articles and documents
Novel synthetic route for antimalarial benzo[a]phenoxazine derivative SSJ-183 and two active metabolites
Mizukawa, Yuki,Ge, Jian-Feng,Bakar Md, Abu,Itoh, Isamu,Scheurer, Christian,Wittlin, Sergio,Brun, Reto,Matsuoka, Hiroyuki,Ihara, Masataka
, p. 3749 - 3752 (2014)
A productive synthesis of benzo[a]phenoxazine derivative SSJ-183 (1), a promising lead for antimalarial agents, was developed using a one pot procedure. Furthermore, N-deethylated metabolite 3 and bis-N,N-deethylated metabolite 4 were synthesized by the application of the method. The metabolites 3 and 4 showed comparable and ～2-fold increased activities against drug-sensitive and drug-resistant Plasmodium falciparum parasites.
Photoelectrochemistry in Colloidal Systems. Part 2. - A Photogalvanic Cell Based on TiO2 Semiconductor Colloid
Kamat, Prashant V.
, p. 509 - 518 (2007/10/02)
Thiazine and oxazine dyes have been photoelectrochemically reduced in colloidal TiO2 suspensions with bandgap excitation.The one-electron reduction of the dye, which resulted in the production of the semireduced radical ion, with quantum yield up to 0.1, further disproportionated to yield a stable leuco dye.The efficiency of the interfacial electron-transfer process is found to be dependent on the standard reduction potential of the dye.The feasibility of employing a colloidal semiconductor system in the operation of a photogalvanic cell is demonstrated.A photogalvanic power conversion efficiency of 0.002percent was achieved with thionine and colloidal TiO2 upon bandgap excitation.The use of TiO2 colloid as a carrier for the deposition of a photoactive or an electroactive species on the electrode surface is also discussed.
