78503-23-8

Upstream product

• 792139-35-6 1-benzhydryl-3-benzhydryloxy-azetidine 
• 91-01-0 1,1-Diphenylmethanol 

Downstream Products

• 1042414-30-1 N-(3-benzhydryloxy-azetidine-1-carbonyl)-4-trifluoromethyl-benzenesulfonamide 
• 1042414-28-7 N-(3-benzhydryloxy-azetidine-1-carbonyl)-4-chloro-benzenesulfonamide 

Relevant academic research and scientific papers

Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors

Fine-tuning than complete disruption of 2-arachidonoylglycerol (2-AG) metabolism in the brain represents a promising pharmacological approach to limit potential untoward effects associated with complete blockade of monoacylglycerol lipase (MGL), the prima

HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST

A heterocyclic compound useful as an antiallergic agent is provided. A compound represented by the following formula (1) or a salt thereof: wherein the ring A is a homocyclic or heterocyclic ring; the ring B is a heterocyclic ring which contains G and nitrogen atom N as constituent atoms thereof, wherein G is CH or N; R1 is a carbonyl group or an alkylene group; R2a and R2b are an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; X is an oxygen atom or a sulfur atom; Z is a hydroxyl group, an alkoxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, an amino group, or an N-substituted amino group; and n is 0 or 1; with the proviso that when the ring A is a benzene ring or when the ring B is a piperazine ring, R1 is an alkylene group which may have a substituent.

Convenient synthesis of structurally novel 1,3-disubstituted azetidine derivatives

A convenient synthesis of structurally novel 1,3-disubstituted azetidine derivatives is described. The approach involves condensation of an azetidine building block with sulfonylated carbamic acid methyl ester, subsequently followed by quenching the imidoyl chloride with amines. Different derivatives were prepared by substituting benzhydrol as well as benzenesulfonamide as part of the core structure. Copyright Taylor & Francis Group, LLC.

N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics

N-(diphenylmethoxy-mono- or bicyclic-alkyleneiminoalkyl)-dicarboximides, e.g. those of the formula STR1 A=aliphatic or cycloaliphatic radical R,R'=H, alkyl, halogen or CF3 R"=H or both are ethylene q=2-4 and salts thereof are antiallergics and antiasthmatics.