78503-95-4Relevant academic research and scientific papers
Dealkylative functionalization of tertiary amines with electron deficient heteroaryl chlorides
Hamilton, Gregory L.,Backes, Bradley J.
, p. 2229 - 2231 (2007/10/03)
The selective dealkylative arylation of trialkyl amines, N-alkyl pyrrolidines, N-alkyl piperidines and dialkyl anilines with electron deficient heteroaryl chlorides was investigated. Efficient and practical reaction conditions were determined for a range
The Synthesis of Alkyl- and Aryl-Substituted 1,3,5-Triazines
Harris, Roger L. N.
, p. 623 - 634 (2007/10/02)
The reaction of chloromethyleneiminium salts with N-cyanoamidines provides a new and versatile route to alkyl- and aryl-substituted 1,3,5-triazines.Variation of substituents in the starting materials allows the synthesis of monoaryl-, diaryl-, alkyl-aryl- and certain mono- and di-alkyl-1,3,5-triazines bearing a variety of other substituents including hydrogen, chlorine and O-, S- and N-radicals.The generally good yields, ready availability of starting materials, and the scope and facility of the reaction make it the method of choice for the synthesis of 1,3,5-triazines with these substitution patterns.
