78508-22-2

Basic information

• Product Name: β-dimethylamino-2-nitrostyrene
• Synonyms: β-dimethylamino-2-nitrostyrene
• CAS NO: 78508-22-2
• Molecular Weight: 271.114
• Mol File: 78508-22-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: β-dimethylamino-2-nitrostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: β-dimethylamino-2-nitrostyrene(78508-22-2)
• EPA Substance Registry System: β-dimethylamino-2-nitrostyrene(78508-22-2)

Safety Data

• Hazardous Substances Data: 78508-22-2(Hazardous Substances Data)

Upstream product

• 119-32-4 4-Methyl-3-nitroanilin 
• 60956-26-5 4-bromo-2-nitrotoluene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 929606-26-8 (2E)-3-(2-amino-4-bromophenyl)-2-(4-chlorophenyl)prop-2-enoic acid 
• 929606-23-5 (2E)-3-(4-bromo-2-nitrophenyl)-2-(4-chlorophenyl)prop-2-enoic acid 
• 929606-25-7 (2E)-3-(2-amino-4-bromophenyl)-2-(4-bromophenyl)prop-2-enoic acid 
• 929606-22-4 (2E)-3-(4-bromo-2-nitrophenyl)-2-(4-bromophenyl)prop-2-enoic acid 
• 207792-73-2 4'-Ethoxy-2-(4''-bromo-2''-nitrophenyl)acetophenone 
• 61-54-1 tryptamine 
• 96624-18-9 6-bromotryptamine 
• 319493-07-7 3-(2-nitrovinyl)-6-bromo-1H-indole 
• 5551-12-2 4-bromo-2-nitrobenzaldehyde 
• 52415-29-9 6-bromo-1H-indole 

Relevant articles and documents

Concerning the preparation of 6-bromotryptamine

Most of the previous syntheses of the marine natural product 6-bromotryptamine have almost certainly led to partial debromination resulting in an impure product containing tryptamine. We show that loss of bromine occurs when lithium aluminum hydride is employed as a reducing agent in the final reaction step leading to 6-bromotryptamine. Reductive-debromination is also likely to intrude during some of the syntheses of 6-bromoindole, the typical precursor to 6-bromotryptamine. None of the seven described syntheses of 6-bromotryptamine that involve a reduction sequence from 6-bromoindole have reported elemental analyses as a measure of purity.

Radioprotectors

A compound of the formula (Ib): wherein X is NCH3, Y is N, Z is N, R3 is N(CH3)2, and (a) R1 is CH3, R2, R4 and R5 to R11 are hydrogen or (b) R5 is CH3 and R1, R2, R4 and R6 to R11 are hydrogen, and salts and tautomers thereof.

Chemical compounds

Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents.