78517-66-5Relevant academic research and scientific papers
Synthesis and reactions of 3,7-cycloerythrinans: Skeletal rearrangement of 2,7,8-trioxoerythrinans to 4-oxo-4H-pyrido[2,1-a]isoquinolines
Tsuda,Sakai,Sano,Toda
, p. 1402 - 1406 (2007/10/02)
Treatment of 2,7,8-trioxoerythrinan derivatives with anhydrous phosphoric acid or Lewis acids gave 3,7-cycloerythrinan derivatives via an intramolecular aldol condensation. The structures of the products were established by spectroscopic and chemical means. Further treatment of the 3,7-cycloerythrinans with anhydrous phosphoric acid resulted in skeletal rearrangement to yield 6,7-dihydro-4-oxo-4H-pyrido[2,1-a]isoquinolines, whose structures were also determined mainly by spectroscopic means.
A NOVEL REARRANGEMENT OF AN 6-ETHOXYCARBONYL-2,7,8-TRIOXOERYTHRINAN TO AN ISOQUINOLINO-α-PYRIDONE DERIVATIVE
Tsuda, Yoshisuke,Sakai, Yuki,Sano, Takehiro
, p. 1097 - 1100 (2007/10/02)
Acid catalysed cyclization of the dioxopyrroline derivative 1b smoothly gave the 2-oxoerthrinan derivative 2b after deacetalization of the intermediate 5.Further acid treatment of 2b gave the pentacyclic compound 7 which could rearrange into an isoquinoli
