78521-41-2Relevant academic research and scientific papers
Structure-based design, synthesis of novel probes for cytochrome P450 OleT
Ma, Dumei,Zhang, Libo,Yin, Yingwu,Wang, Qian
supporting information, p. 1466 - 1469 (2020/11/12)
Cytochrome P450 OleTSA, a new cytochrome P450 enzyme from Staphylococcus aureus, catalyzes the oxidative decarboxylation and hydroxylation of fatty acids to generate terminal alkenes and fatty alcohols. The mechanism of this bifurcative chemist
2-Oxoamide inhibitors of cytosolic group IVA phospholipase A2with reduced lipophilicity
Antonopoulou, Georgia,Magrioti, Victoria,Kokotou, Maroula G.,Nikolaou, Aikaterini,Barbayianni, Efrosini,Mouchlis, Varnavas D.,Dennis, Edward A.,Kokotos, George
, p. 4544 - 4554 (2016/09/13)
Cytosolic GIVA phospholipase A2(GIVA cPLA2) initiates the eicosanoid pathway of inflammation and thus inhibitors of this enzyme constitute novel potential agents for the treatment of inflammatory diseases. Traditionally, GIVA cPLAsu
