78533-92-3

Upstream product

• 1133712-62-5 2-(3-methoxyphenyl)propane-1,3-diazide 
• 78533-78-5 3-(3-methoxyphenyl)glutaronitrile 
• 78533-88-7 3-(3-methoxyphenyl)glutaramide 

Downstream Products

• 78533-69-4 2-methoxycarbonylamino-5-(3-methoxyphenyl)-1,4,5,6-tetrahydropyrimidine 
• 1133712-89-6 (R)-(-)-allyl (3-amino-2-(3-methoxyphenyl)propyl)carbamate 
• 1133713-28-6 N-(3-amino-2-(3-methoxyphenyl)propyl)acetamide 

Relevant academic research and scientific papers

Enzymatic desymmetrization of prochiral 2-substituted-1,3-diamines: Preparation of valuable nitrogenated compounds

A wide range of prochiral 1, 3-diamines were first efficiently synthesized and subsequently desymmetrized by using lipase from Pseudomonas cepacia as catalyst and diallyl carbonate as alkoxycarbonylating agent. In all cases, the amino carbamates of R-configuration were recovered. Final selective cleavage of the N-allyloxycarbonyl moiety was carried out under mild reaction conditions, which demonstrates the high versatility and potential of this chemoenzymatic route as a source of intermediates in the synthesis of related optically active nitrogenated derivatives.

Synthesis and Antidepressant Profiles of Phenyl-Substituted 2-Amino- and 2--1,4,5,6-tetrahydropyrimidines

A series of 4(6)- and 5-phenyl-substituted 2-amino- and 2-(alkoxycarbonyl)amino-1,4,5,6-tetrahydropyrimidines 2 were prepared and evaluated for central nervous system (CNS) effects in animal models.Several 5-phenyl-substituted compounds possessed potent

4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives

Certain 1,4,5,6-tetrahydropyrimidine compounds which are substituted with an amino, amido or carbamate at the 2-position, with an optionally substituted phenyl at the 5-position or at the 4-position when there is no alkyl at the 1-position and optionally