78554-68-4Relevant articles and documents
Synthesis method of arylimidazophenanthroline fluorescence dye, and recognition of metal ions
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, (2020/02/20)
The invention discloses a synthesis method of an arylimidazophenanthroline fluorescence dye, and recognition of metal ions. The synthesis method is a method for synthesizing arylimidazo[4,5-f]phenanthroline oxa-crown ether compounds from cheap and easily available 1,10-phenanthroline through a series of steps. Fluorescence properties of the arylimidazo[4,5-f]phenanthroline compounds are screened,the complexing property of the compounds and metal ions is verified through screening experiments of different metal ions and experiments of ion concentration and the like, and recognition of the metal ions Zn in tumor cells is achieved. The fluorescence probe has the following technical effects: 1, the compounds respectively have high selectivity to Zn Zn on wide metal ions; and 2, a fluorescence quenching molecular switch responding to Zn can be obtained in MCF-7 cells, and lays a great foundation for the application of the system in fields of biological recognition and the like.