78558-65-3Relevant academic research and scientific papers
Alpha-thio-alpha-aryl-substituted alkanonitrile and process for preparing alpha-aryl-substituted alkanonitrile therefrom
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, (2008/06/13)
An alpha-thio-alpha-aryl-substituted alkanonitrile of the general formula STR1 wherein Ar represents an aromatic group, R represents a hydrogen atom or an alkyl group, R1 represents an alkyl group or an aromatic group, and Y represents an oxygen atom or a carbonyl group. The above compound can be prepared by reacting an alpha-aryl-substituted-alpha-thio-acetonitrile of the general formula STR2 wherein Ar, Y and R1 are as defined above, with an alkylating agent in the presence of a strong base. This compound is useful as an intermediate for producing an alpha-aryl-substituted alkane-carboxylic acid of the general formula STR3 wherein Ar, Y and R1 are as defined above.
