785777-90-4

Basic information

• Product Name: 5-BroMo-4-(trifluoroMethyl)pyriMidin-2(1H)-one
• Synonyms: 5-BroMo-4-(trifluoroMethyl)pyriMidin-2(1H)-one
• CAS NO: 785777-90-4
• Molecular Formula: C5H2BrF3N2O
• Molecular Weight: 242.9813896
• Product Categories: alkyl bromide
• Mol File: 785777-90-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 5-BroMo-4-(trifluoroMethyl)pyriMidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-4-(trifluoroMethyl)pyriMidin-2(1H)-one(785777-90-4)
• EPA Substance Registry System: 5-BroMo-4-(trifluoroMethyl)pyriMidin-2(1H)-one(785777-90-4)

Safety Data

• Hazardous Substances Data: 785777-90-4(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-(trifluoromethyl)pyrimidin-2(1H)-one is an organic compound that belongs to the category of pyrimidine derivatives. It is characterized by a pyrimidine ring with a bromine and a trifluoromethyl group attached to it. This chemical is commonly used in the synthesis of pharmaceutical compounds and agrochemicals due to its versatile reactivity and stability. Additionally, it has been studied for its potential applications in the field of medicinal chemistry, particularly for its anticancer and antiviral properties. 5-Bromo-4-(trifluoromethyl)pyrimidin-2(1H)-one is a valuable building block for the development of new drugs and biologically active molecules.

Upstream product

• 104048-92-2 4-(trifluoromethyl)-2-pyrimidinol 
• 104048-92-2 4-(trifluoromethyl)pyrimidin-2(1H)-one 

Downstream Products

• 785777-92-6 5-bromo-2-chloro-4-(trifluoromethyl)pyrimidine 
• 785777-91-5 2,5-dibromo-4-(trifluoromethyl)pyrimidine 

Relevant articles and documents

COMPOUNDS FOR USE IN TREATING ACUTE CORONARY SYNDROME AND RELATED CONDITIONS

Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.

Brominated 4-(trifluoromethyl)pyrimidines: A convenient access to versatile intermediates

An expedient route to all three monobrominated and all three dibrominated isomers of 4-(trifluoromethyl)pyrimidine, and to several other halogenated pyrimidines, is described. Key steps are the electrophilic introduction of the halogen in the 5-position of 2- or 4-pyrimidinones, the bromodeoxygenation of pyrimidinones or thiopyrimidinones using phosphorus tribromide, and the partial debromination of dibromo-4-(trifluoromethyl)pyrimidines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.