785793-89-7Relevant articles and documents
Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitors
Reddy, M.V. Ramana,Mallireddigari, Muralidhar Reddy,Pallela, Venkat R.,Venkatapuram, Padmavathi,Boominathan, Rengasamy,Bell, Stanley C.,Reddy, E. Premkumar
, p. 1715 - 1723 (2008/02/02)
A new series of styryl acetoxyphenyl sulfides and sulfones possessing (E)- and (Z)-configurations were designed and prepared by stereospecific syntheses. All these compounds were evaluated for their ability to inhibit COX-2 enzyme in vitro. Structure-acti