78589-15-8

Basic information

• Product Name: 1-(4-dimethylamino-2-methoxyphenyl)ethanone
• Synonyms: 1-(4-dimethylamino-2-methoxyphenyl)ethanone
• CAS NO: 78589-15-8
• Molecular Weight: 193.246
• Mol File: 78589-15-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-dimethylamino-2-methoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-dimethylamino-2-methoxyphenyl)ethanone(78589-15-8)
• EPA Substance Registry System: 1-(4-dimethylamino-2-methoxyphenyl)ethanone(78589-15-8)

Safety Data

• Hazardous Substances Data: 78589-15-8(Hazardous Substances Data)

Usage

General Description

1-(4-dimethylamino-2-methoxyphenyl)ethanone, also known as DMAP, is a chemical compound with the molecular formula C11H15NO2. 1-(4-dimethylamino-2-methoxyphenyl)ethanone is a ketone and is commonly used as a reagent and catalyst in organic synthesis. It is known for its ability to catalyze the acylation of alcohols and amines, and is often used in the production of pharmaceuticals and agrochemicals. DMAP is a pale yellow solid with a melting point of 66-68 °C, and has a characteristic amine odor. It is considered to be a stable compound with low reactivity, making it a valuable tool in organic chemistry research.

Upstream product

• 107070-69-9 1-(4-(dimethylamino)-2-hydroxyphenyl)ethanone 
• 17579-36-1 m-NMe₂C₆H₄OAc 
• 74-88-4 methyl iodide 
• 60207-18-3 4'-amino-2'-methoxylacetophenone 

Downstream Products

• 1021493-91-3 (E)-3-(4-bromophenyl)-1-(4-(dimethylamino)-2-methoxyphenyl)prop-2-en-1-one 
• 1448349-18-5 (E)-1-(4-(dimethylamino)-2-methoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one 
• 1448349-17-4 (E)-1-(4-(dimethylamino)-2-methoxyphenyl)-3-(5-methylfuran-2-yl)prop-2-en-1-one 

Relevant articles and documents

Synthesis and identification of new flavonoids targeting liver X receptor β involved pathway as potential facilitators of Aβ clearance with reduced lipid accumulation

Alzheimer's disease (AD) is associated with impaired Aβ degradation in the brain. Enhancing the process of Aβ clearance is an attractive potential AD therapy. Treatment with LXR agonists may reduce Aβ levels in vivo. However, the clinical potential of man

Infrared study of polysubstitution effects in benzophenones and acetophenones: contribution of inter and intracycle interaction mechanisms

The carbonyl stretching frequencies of substituted 2-Me, 2,6-diMe, 2-MeO benzophenones and 2-Me, 2-MeO acetophenones have been measured in diluted CCl4 solutions.Two interaction mechanisms are observed.In X, Y substituted benzophenones with X on the same cycle as the ortho group and Y on the other cycle, it is shown that for X=Y, the effect of Y is greater than that of X except for very strong electron-releasing substituents.In this last case, the observed enhancement is attributed to the joint effects of intercycle interactions excercised on X and Y and of intracycle interaction on X.These results are corroborated by the study of substituted acetophenones in which only the intracycle mechanism can play a role.