78592-73-1

Basic information

• Product Name: (3E)-4-iodo-3-methylbut-3-en-1-ol
• CAS NO: 78592-73-1
• Molecular Formula: C₅H₉IO
• Molecular Weight: 212.0288
• Mol File: 78592-73-1.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 218.2°C at 760 mmHg
• Flash Point: 85.7°C
• Density: 1.754g/cm³
• Vapor Pressure: 0.0272mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: (3E)-4-iodo-3-methylbut-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-4-iodo-3-methylbut-3-en-1-ol(78592-73-1)
• EPA Substance Registry System: (3E)-4-iodo-3-methylbut-3-en-1-ol(78592-73-1)

Safety Data

• Hazardous Substances Data: 78592-73-1(Hazardous Substances Data)

Upstream product

• 75-24-1 trimethylaluminum 
• 927-74-2 3-Butyn-1-ol 

Downstream Products

• 88968-96-1 5-((tert-Butyldimethylsilyl)oxy)-3-methyl-2(E)-pentenoic Acid 
• 78592-77-5 (E)-4-tert-butyldimethylsilyloxy-1-iodo-2-methyl-1-butene 
• 1208-86-2 N-(4-methoxyphenyl)phenylamine 

Relevant articles and documents

Efficient assembly of the phomactin core via two different macrocyclization protocols.

[reaction--see text] The core structure of phomactins C and D was assembled by an efficient strategy starting from 3,4-dimethylcyclohexen-2-one. Key reactions include (1) a high yielding and highly diastereoselective Michael addition of a mixed cuprate, (

An efficient and stereoselective synthesis of the monomeric counterpart of marinomycin A

Equation presented The monomeric counterpart of marinomycin A, an antitumor-antibiotic marine natural product, was synthesized efficiently in 11 steps from the commercially available ethyl (R)-(-)-3-hydroxybutyrate. The strategy was highlighted by a cruci

Methyl-Shifted Farnesyldiphosphate Derivatives Are Substrates for Sesquiterpene Cyclases

New sesquiterpene backbones are accessible after biotransformation of presilphiperfolan-8β-ol synthase (BcBOT2), a fungal sesquiterpene synthase, with non-natural farnesyldiphosphates in which methyl groups are shifted by one position toward the diphosphate terminus. One of the macrocycles formed, a new germacrene A derivative, undergoes a Cope rearrangement to iso-β-elemene. Three of the new terpenoids show olfactoric properties that range from an intense peppery note to a citrus, ozone-like, and fruity scent.

Dialkoxycarbenes in (4 + 1) Cycloadditions: Application to the Synthesis of Carotol

Dialkoxycarbenes are more reactive than NHCs and participate in many reactions including a formal (4 + 1) cycloaddition with electron-deficient dienes. We have learned to control the relative stereochemistry of the newly created chiral carbons in this pro