78604-31-6

Basic information

• Product Name: (1E)-1-(2-chloroethyl)-3-(4-nitrophenyl)triaz-1-ene
• CAS NO: 78604-31-6
• Molecular Formula: C₈H₉ClN₄O₂
• Molecular Weight: 228.6357
• Mol File: 78604-31-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 340.1°C at 760 mmHg
• Flash Point: 159.5°C
• Density: 1.41g/cm³
• Vapor Pressure: 8.77E-05mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: (1E)-1-(2-chloroethyl)-3-(4-nitrophenyl)triaz-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-1-(2-chloroethyl)-3-(4-nitrophenyl)triaz-1-ene(78604-31-6)
• EPA Substance Registry System: (1E)-1-(2-chloroethyl)-3-(4-nitrophenyl)triaz-1-ene(78604-31-6)

Safety Data

• Hazardous Substances Data: 78604-31-6(Hazardous Substances Data)

Usage

General Description

The chemical (1E)-1-(2-chloroethyl)-3-(4-nitrophenyl)triaz-1-ene, also known as 2-Chloroethyl 3-(4-Nitrophenyl)-1-Hydroxy-2-Aziridinecarboxylate, is a triazene compound with potential antineoplastic and anti-cancer properties. It is a synthetic alkylating agent that can act as a DNA cross-linking agent. The compound is believed to function by inhibiting DNA replication and inducing cell cycle arrest and apoptosis in cancer cells. It may be utilized in the treatment of various types of cancers, including solid tumors and leukemia, as well as in combination with other chemotherapeutic agents to enhance the overall treatment response. Further research is being conducted to explore the full therapeutic potential and safety profile of this compound.

Upstream product

• 100-01-6 4-nitro-aniline 
• 689-98-5 chloroethylamine 

Relevant articles and documents

Synthesis of 3(2-haloethyl)aryltriazenes and study of their reactions in aqueous solution

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