78605-08-0Relevant academic research and scientific papers
Reactions of β-(lithiomethyl)azines with nitriles as a route to pyrrolo-pyridines, - quinolines, -pyrazines, - quinoxalines and -pyrimidines
Davis, Michael L.,Wakefield, Basil J.,Wardell, Jacklyn A.
, p. 939 - 952 (2007/10/02)
Deprotonation of 3-methylazines, followed by reaction with benzonitile, gives an intermediate which, on treatment with additional strong base, cyclises to give 2-phenyl[1H]-pyrrolo[2,3-b]pyridine. The application of this type of reaction to a variety of n
Cyclisation par amination intramoleculaire dans la serie de la pyrazine.
Vierfond, Jean-Michel,Mettey, Yvette,Mascrier-Demagny, Line,Miocque, Marcel
, p. 1219 - 1222 (2007/10/02)
An original one-pot synthesis of 4,7-diazaindoles is achieved by metalation of methylpyrazines or methylquinoxaline which are then condensed with an aromatic nitrile : an intermediate imine-enamine is formed which leads, by intramolecular cyclization, to diazaindoles.
