78614-48-9

Basic information

• Product Name: Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat
• CAS NO: 78614-48-9
• Molecular Weight: 818.961
• Mol File: 78614-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat(CAS DataBase Reference)
• NIST Chemistry Reference: Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat(78614-48-9)
• EPA Substance Registry System: Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat(78614-48-9)

Safety Data

• Hazardous Substances Data: 78614-48-9(Hazardous Substances Data)

Upstream product

• 42868-97-3 2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl chloride 
• 143-62-4 (+)-digitoxigenin 

Downstream Products

• 78614-49-0 Digitoxigenin-3β-O-α-L-arabinofuranosid 

Relevant articles and documents

Synthesis and properties of digitoxigenin-3β-O-α-L-arabinofuranoside

The synthesis of a cardenolide glycoside with a furanoide sugar component, digitoxigenin-3β-O-α-L-arabinofuranoside (4), is described for the first time. 4 was prepared by the reaction of digitoxigenin with 2,3,5-tri-O-benzoyl-α-L-arabinofuranosylchloride and Fetizon-reagent in benzene/dioxan followed by debenzoylation with ammonia in dry methanol. Compound 4 is cleaved by α-L-arabinofuranosidase (Aspergillus niger K1) into digitoxigenin and L-arabinose. Hydrolytic stability against methanolic HCl (0.1 mol/l) is relatively high. 4.10-8 mol/l 4 gives a 50% inhibition of the Na,K-ATPase (pig heart muscle) and is 2.5 times more active at this receptor than the aglycon digitoxigenin.