78629-19-3 Usage
Uses
Used in Organic Synthesis:
1-BROMO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE is used as a key intermediate in the synthesis of complex organic molecules for various applications, including the creation of new pharmaceuticals and agrochemicals. Its unique structure allows for versatile reactions, making it a valuable component in the development of novel compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-BROMO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE is used as a building block for the synthesis of medicinal compounds. Its presence in the molecular structure can contribute to the desired pharmacological properties of the final drug, such as potency, selectivity, and bioavailability.
Used in Agrochemical Production:
Similarly, in agrochemicals, 1-BROMO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE is employed as a precursor in the synthesis of pesticides, herbicides, and other crop protection agents. Its role in these products is crucial for enhancing their effectiveness and selectivity in agricultural settings.
Used as a Reagent in Chemical Reactions:
1-BROMO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE also serves as a reagent in various chemical reactions, facilitating the formation of desired products. Its reactivity and stability make it suitable for use in a range of laboratory and industrial processes, contributing to the advancement of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 78629-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,6,2 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 78629-19:
(7*7)+(6*8)+(5*6)+(4*2)+(3*9)+(2*1)+(1*9)=173
173 % 10 = 3
So 78629-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H13Br/c1-9(2,3)7-5-4-6-8-10/h4,6H,8H2,1-3H3
78629-19-3Relevant academic research and scientific papers
A stereoselective synthesis of (E)-1-halo-6,6-dimethyl-2-hepten-4-yne: A key intermediate for terbinafine
Chou, Shan-Yen,Tseng, Chin-Lu,Chen, Shyh-Fong
, p. 3895 - 3898 (2007/10/03)
A study of the stereoselective halogenation of 6,6-dimethyl-1-hepten-4- yn-3-ol (1) using a series of halogenating agents is described. Of the many agents investigated, boron trichloride is the most successful reagent for stereoselective halogenation (E:Z=9:1(max)). The resulting (E)-1-halo-6,6- dimethyl-2-hepten-4-yne (2), a key intermediate for terbinafine, an antifungal agent, is obtained in good yield and stereoselectivity. Two structurally related enyne alcohols have been studied likewise and shown similar versatility. (C) 2000 Elsevier Science Ltd.
Synthesis and Antifungal Activity of (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine (SF 86-327) and Related Allylamine Derivatives with Enhanced Oral Activity
Stuetz, Anton,Petranyi, Gabor
, p. 1539 - 1543 (2007/10/02)
The allylamine derivatives are a new class of synthetic antifungal agents inhibiting fungal squalene epoxidase.A new subclass, which features an acetylene group conjugated with the allylamine double bond, is characterized by enhanced antifungal activity, especially on oral treatment of guinea pig dermatophytoses.Increased branching of the alkyl group next to the triple bond led to the tert-butylacetylene derivative SF 86-327, a compound with strikingly increased activity in vitro and in vivo, which is now under clinical evaluation.Versatile synthetic routes, comparative biological data, and structure-activity relationship are presented.
