78662-46-1Relevant academic research and scientific papers
Synthesis of bis-Schiff bases of isatins and their antiglycation activity
Khan, Khalid Mohammed,Khan, Momin,Ali, Muhammad,Taha, Muhammad,Rasheed, Saima,Perveen, Shahnaz,Choudhary, M. Iqbal
, p. 7795 - 7801 (2009)
Bis-Schiff bases 1-27 have been synthesized and their in vitro antiglycation potential has been evaluated. Compounds 21 (IC50 = 243.95 ± 4.59 μM), 20 (IC50 = 257.61 ± 5.63 μM), and 7 (IC50 = 291.14 ± 2.53 μM) showed an exc
Application of SBA-Pr-SO3H in the green synthesis of isatinhydrazone derivatives: Characterization, UV-Vis investigation and computational studies
Gholamzadeh, Parisa,Mohammadi Ziarani, Ghodsi,Badiei, Alireza
, p. 2935 - 2939 (2016/10/06)
An efficient and green synthesis is developed for the preparation of the arylidene isatinhydrazone derivatives 4a-m using a heterogeneous mesoporous acid catalyst of SBA-Pr-SO3H with a pore size of 6 nm under solvent free conditions. The hydrazones 4a-m were then analyzed by UV-Vis spectroscopy and the results were used for the calculation of the HOMO-LUMO band gap. In addition, the quantum chemical calculations were performed to provide an illustrative explanation for the obtained band gap; it is found that probably these molecules have a high tendency to donate electrons to the appropriate small-molecule acceptors with low energy and empty molecular orbital.
Synthesis leishmanicidal activities of bis-Schiff bases of isatins
Khan, Momin,Khan, Khalid Mohammed,Rahim, Fazal,Samreen,Perveen, Shahnaz,Karim, Aneela,Imtiazuddin,Choudhary, Muhammad Iqbal
, p. 520 - 526 (2015/08/04)
Twenty seven (27) derivatives of bis-Schiff bases of isatins 1-27 were studied for their leishmanicidal potential. Out of twenty seven (27) analogs, five exhibited varying degree of leishmanicidal activity with IC50 values 44.86 ± 0.66, 65.27 ±
Superoxide respiratory burst inhibitory activity of bis-schiff bases of Isatins
Khan, Khalid Mohammed,Khan, Momin,Ali, Muhammad,Qadir, Muhammad Irfan,Perveen, Shahnaz,Karim, Aneela,Choudhary, Muhammad Iqbal
, p. 987 - 993 (2013/07/26)
Bis-Schiff bases 1-27 were synthesized and evaluated for their anti-inflammatory activity and possible cytotoxicity. Compounds 1-27 showed a varying degree of respiratory burst inhibitory activity with IC50 values between 242.97 - 652.12 μM. Co
