786686-82-6

Basic information

• Product Name: N-DEMETHYLOLANZAPINE-D8
• Synonyms: N-DEMETHYLOLANZAPINE-D8;2-Methyl-4-(1-piperazinyl)-10H-Thieno[2,3-b][1,5]benzodiazepine-d8;4'-DesMethylolanzapine-d8;DesMethylolanzapine-d8;LY 170055-d8
• CAS NO: 786686-82-6
• Molecular Formula: C16H17N4S
• Molecular Weight: 297.39798
• Product Categories: Isotope Labeled Compounds;Metabolites;Isotope Labelled Compounds;Isotope Labelled Compounds, Metabolites
• Mol File: 786686-82-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 129-131°C (dec.)
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated)
• CAS DataBase Reference: N-DEMETHYLOLANZAPINE-D8(CAS DataBase Reference)
• NIST Chemistry Reference: N-DEMETHYLOLANZAPINE-D8(786686-82-6)
• EPA Substance Registry System: N-DEMETHYLOLANZAPINE-D8(786686-82-6)

Safety Data

• Hazardous Substances Data: 786686-82-6(Hazardous Substances Data)

Usage

Description

N-DEMETHYLOLANZAPINE-D8 is a deuterated and labeled metabolite of Olanzapine, a pharmaceutical compound primarily used for the treatment of schizophrenia and bipolar disorder. It is characterized by its brown solid appearance and is utilized in various applications across different industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
N-DEMETHYLOLANZAPINE-D8 is used as a labeled metabolite for Olanzapine in the pharmaceutical industry. It serves as a valuable tool in research and development, enabling scientists to study the metabolic pathways and pharmacokinetics of Olanzapine. This information is crucial for understanding the drug's efficacy, safety, and potential side effects, ultimately leading to the optimization of therapeutic strategies for patients.
Used in Research and Development:
In the field of research and development, N-DEMETHYLOLANZAPINE-D8 is used as a labeled compound to investigate the mechanisms of action and potential interactions of Olanzapine with biological systems. This can help in the discovery of new therapeutic targets and the development of novel drugs with improved efficacy and safety profiles.
Used in Quality Control and Analytical Testing:
N-DEMETHYLOLANZAPINE-D8 is also used as a reference material in quality control and analytical testing within the pharmaceutical industry. It helps ensure the accuracy and reliability of analytical methods used to determine the purity, potency, and stability of Olanzapine and its related compounds.
Used in Forensic Toxicology:
In forensic toxicology, N-DEMETHYLOLANZAPINE-D8 can be employed as an internal standard for the quantification of Olanzapine and its metabolites in biological samples. This aids in the investigation of cases involving drug-related fatalities, drug abuse, or the presence of drugs in the body for legal purposes.
Used in Environmental Monitoring:
Although not explicitly mentioned in the provided materials, N-DEMETHYLOLANZAPINE-D8 could potentially be used in environmental monitoring to track the presence and distribution of Olanzapine and its metabolites in the environment. This information can be valuable for assessing the environmental impact of pharmaceuticals and developing strategies to mitigate their effects.