786701-13-1

Basic information

• Product Name: GW 876008X
• CAS NO: 786701-13-1
• Molecular Weight: 404.472
• Mol File: 786701-13-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: GW 876008X(CAS DataBase Reference)
• NIST Chemistry Reference: GW 876008X(786701-13-1)
• EPA Substance Registry System: GW 876008X(786701-13-1)

Safety Data

• Hazardous Substances Data: 786701-13-1(Hazardous Substances Data)

Usage

General Description

GW 876008X, also known as 3-(2-Methyl-1-(2-naphthoyl)-1H-indol-3-yl)-N-phenylacrylamide, is a synthetic drug that acts as a potent and selective agonist for the cannabinoid receptor CB2. It has been shown to have anti-inflammatory and analgesic effects in preclinical studies, making it a potential candidate for the treatment of various conditions such as chronic pain, inflammation, and neurodegenerative diseases. GW 876008X has also been investigated for its potential use in cancer therapy, as it has shown promise in inhibiting the growth of cancer cells in vitro. Further research is needed to better understand the full therapeutic potential of this compound and its possible side effects.

Upstream product

• 727993-66-0 1-[2-methyl-4-(methyloxy)phenyl]-2-pyrrolidinone 
• 727993-68-2 6-methyl-1-[2-methyl-4-(methyloxy)phenyl]-1,2,3,7-tetrahydro-4H-pyrrolo[2,3-b]pyridin-4-one 
• 727993-69-3 6-methyl-1-[2-methyl-4-(methyloxy)phenyl]-1,2,3,7-tetrahydro-4H-pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate 
• 1235407-66-5 1-(4-methoxy-2-methylphenyl)pyrrolidin-2-imine hydrobromide 
• 727993-67-1 ethyl 3-({1-[2-methyl-4-(methyloxy)phenyl]-2-pyrrolidinylidene}amino)-2-butenoate 
• 102-50-1 2-methyl-4-methoxyaniline 
• 1092380-15-8 4-chloro-N-[2-methyl-4-(methyloxy)phenyl]butanamide 
• 727993-70-6 4-iodo-6-methyl-1-[2-methyl-4-(methyloxy)phenyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine 
• 1235407-68-7 C₈H₁₀N₄O₂ 
• 785834-43-7 N-(2-chloroethyl)-3-({[(2-chloroethyl)amino]carbonyl}amino)-1H-pyrazole-1-carboxamide 
• 785834-47-1 1-(1H-pyrazol-3-yl)-2-imidazolidinone 
• 785834-45-9 N-(2-chloroethyl)-3-(2-oxo-1-imidazolidinyl)-1H-pyrazole-1-carboxamide 

Relevant articles and documents

Identification of a manufacturing route of novel CRF-1 antagonists containing a 2,3-Dihydro-1 H-pyrrolo[2,3-b]pyridine moiety

A case study on the synthesis of novel CRF-1 antagonists containing the 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine moiety is presented. The development of ever more efficient synthetic routes allowed the progression of three candidates at the same time. A manu

PROCESS FOR PREPARING BICYCLIC COMPOUNDS

The present invention relates to a process for preparing compounds of formula (IA), which are potent and specific antagonists of corticotropin-releasing factor (CRF) receptors, from intermediate compounds of formula (I), by a coupling reaction catalysed b