786703-40-0Relevant academic research and scientific papers
Synthesis and properties of oligodeoxyribonucleotides containing 2′-O-(2,3-dihydroxypropyl)- and 2′-O-(2-oxoethyl)arabinouridine residues
Zatsepin,Ivanova,Stetsenko,Gait,Oretskaya
, p. 238 - 246 (2007/10/03)
2′-O-(2,3-Dihydroxypropyl)arabinouridine-containing oligodeoxyribonucleotides were synthesized starting from a new modified nucleoside, viz., 2′-O-(2,3-dihydroxypropyl)arabinouridine, and the corresponding 3′-phosphoramidite. Oxidation of these oligodeoxy
Efficient conjugation and preferential DNA binding of oligonucleotides containing 2′-O-(2-oxoethyl)arabinouridine
Zatsepin, Timofei S.,Ivanova, Yulia M.,Stetsenko, Dmitry A.,Gait, Michael J.,Oretskaya, Tatiana S.
, p. 7327 - 7330 (2007/10/03)
Oligodeoxyribonucleotides were synthesized that contain a novel nucleoside, 2′-O-(2-oxoethyl)arabinouridine. Whereas such oligonucleotides showed only a slight reduction in the TM values of their complexes with complementary DNA, a significant
