786709-64-6Relevant academic research and scientific papers
Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphoric acid analogues as alternate substrates for methylerythritol phosphate synthase
Fox, David T.,Poulter, C. Dale
, p. 1978 - 1985 (2007/10/03)
(Chemical Equation Presented) Four deoxyxylulose phosphate (DXP) analogues were synthesized and evaluated as substrates/ inhibitors for methylerythritol phosphate (MEP) synthase. In analogues CF3-DXP (1), CF 2-DXP (2), and CF-DXP (3)
Study of 1-deoxy-D-xylulose-5-phosphate reductoisomerase: Synthesis and evaluation of fluorinated substrate analogues
Wong, Alexander,Munos, Jeffrey W.,Devasthali, Vidusha,Johnson, Kenneth A.,Liu, Hung-Wen
, p. 3625 - 3628 (2007/10/03)
(Chemical Equation Presented) 1-Deoxy-D-xylulose-5-phosphate (DXP) reductoisomerase is a NADPH-dependent enzyme catalyzing the conversion of DXP to methyl-D-erythritol 4-phosphate (MEP). In this study, each of the hydroxyl groups in DXP and one of its C-1
