78682-47-0

Usage

Category

Alcohols and Phenols

Physical state

Colorless liquid

Odor

Slightly sweet, floral

Uses

a. Perfumes and fragrances
b. Pharmaceutical industry
c. Flavoring agent in food products

Applications

Development of various consumer products due to its unique chemical structure

Upstream product

• 78-77-3 Isobutyl bromide 
• 591-31-1 3-methoxy-benzaldehyde 
• 27720-98-5 isobutylmagnesium iodide 
• 766-85-8 3-methoxy-1-iodobenzene 
• 590-86-3 isovaleraldehyde 
• 926-62-5 isobutylmagnesium bromide 

Downstream Products

• 78682-48-1 1-(1-Chloro-3-methyl-butyl)-3-methoxy-benzene 
• 78682-41-4 C₂₄H₃₄O₂ 
• 1183770-52-6 3-methyl-1-[3-(methyloxy)phenyl]-1-butanone 
• 1312594-21-0 {3-methyl-1-[3-(methyloxy)phenyl]butylidene}propanedinitrile 
• 1312594-22-1 2-amino-5-(1-methylethyl)-4-[3-(methyloxy)phenyl]-3-thiophenecarbonitrile 
• 1607462-14-5 C₂₃H₂₀N₄O₃S 
• 1607462-13-4 C₂₂H₂₀IN₃O₃S 
• 1607461-52-8 C₂₂H₂₀ClN₃O₃S 
• 1607462-04-3 C₁₃H₁₄ClNOS 
• 1607462-03-2 C₁₃H₁₅NO₂S 
• 1310254-19-3 C₁₂H₁₅BrO₂ 
• 1607461-45-9 C₂₂H₂₁N₃O₅S₂ 
• 1607461-42-6 C₂₂H₁₈F₃N₃O₃S 
• 1607461-50-6 C₂₆H₂₆F₃N₅O₂S 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES OR DISORDERS ASSOCIATED WITH MISREGULATED EIF4E

Disclosed herein are compounds, compositions, formulations, kits and methods of treatment useful for treating or preventing one or more hyperproliferative disorders, e.g., cancer or a neurological disease or disorder.

NOVEL COMPOUNDS

The present invention relates to novel NADPH oxidase II inhibitors and their use in the treatment of diseases mediated by the NADPH oxidase II enzyme.

Activation of functional arylzincs prepared from aryl iodides and highly enantioselective addition to aldehydes

(Chemical Equation Presented) An easily available chiral ligand (S)-1 is found to activate the nucleophilic reaction of the arylzincs prepared in situ from the reaction of aryl iodides with Et2Zn. Both high yields and high enantioselectivity (u

Influence of Alkyl Chain Ramification on Estradiol Receptor Binding Affinity and Intrinsic Activity of 1,2-Dialkylated 1,2-Bis(4- or 3-hydroxyphenyl)ethane Estrogens and Antiestrogens

The influence of a symmetrical introduction of CH3 substituents in the α or β positions of the 1,2-dialkyl-1,2-bis(4-hydroxyphenyl)ethene estrogens hexestrol (ethyl, HES) and octestrol (n-propyl, OCES) isopropyl (1), tert-butyl (2), sec-butyl (3), isobut

Potential Antiestrogens. Synthesis and Evaluation of Mammary Tumor Inhibiting Activity of 1,2-Dialkyl-1,2-bis(3'-hydroxyphenyl)ethanes

The syntheses of the meso-1,2-dialkyl-1,2-bis(3'-hydroxyphenyl)ethanes and of d,l-3,4-bis(3'-hydroxyphenyl)hexane (21) are described.In vitro these compounds inhibited the estradiol receptor interaction competitively, exhibiting Ka values between 0.20*109 (20) and 0.11*106 M-1 (24).In vivo the meso compounds reduced the estrone-stimulated mouse uterine growth; the most effective compounds were 20, 22, and 23 (53, 50, and 45percent inhibition, respectively).Compounds 20 and 22-24 showed weak estrogenic activity in the mouse uterine weight test and in the vaginal cornification test.Compounds 19 (NSC-297169), 20 (NSC-297170), and 22 (NSC-297171) exhibited a dose-dependent growth inhibition on the MCF-7 human breast tumor cell line (10-6 to 10-9 M).These compounds also showed a marked dose-dependent inhibition on the DMBA-induced, hormone-dependent mammary carcinoma of the Sprague-Dawley rat corresponding to their association constants.