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Usage

Uses

Used in Pharmaceutical Synthesis:
1 beta-D-ribofuranosylpyridin-4-one 3-carboxamide is used as a precursor in the pharmaceutical industry for the synthesis of various pharmaceuticals and chemical compounds. Its unique structure and properties make it a valuable building block for developing new drugs and therapies.
Used in Energy Metabolism:
In the biological field, 1 beta-D-ribofuranosylpyridin-4-one 3-carboxamide is used as a key component in energy metabolism, contributing to the production of energy within cells and the overall functioning of metabolic pathways.
Used in Treatment of Vitamin B3 Deficiencies:
1 beta-D-ribofuranosylpyridin-4-one 3-carboxamide is used as a therapeutic agent for the treatment of conditions such as pellagra and other vitamin B3 deficiencies. Its role in coenzyme synthesis helps address the underlying causes of these deficiencies and improve the health of affected individuals.
Used in Nucleic Acid Metabolism Research:
1 beta-D-ribofuranosylpyridin-4-one 3-carboxamide is used in the study of nucleic acid metabolism, providing insights into the activity of enzymes involved in the biosynthesis of important coenzymes. This research can lead to a better understanding of cellular processes and the development of targeted therapies for various diseases.
Overall, 1 beta-D-ribofuranosylpyridin-4-one 3-carboxamide is a versatile and significant compound with applications in pharmaceutical synthesis, energy metabolism, treatment of vitamin B3 deficiencies, and research on nucleic acid metabolism.

Upstream product

• 62410-12-2 1,5-di-O-acetyl-2,3-O-isopropylidene-β-D-ribofuranose 
• 89640-65-3 3-carboxamido-4-pyridone 
• 1337988-82-5 4-pyridone-3-(carboxylic acid)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranoside) 
• 28708-32-9 1,2,3,5-tetra-O-acetyl-D-ribofuranose 

Relevant academic research and scientific papers

Isolation and characterization of an unusual nucleoside, 1-α-D- ribofuranosyl-4-pyridone-3-carboxamide, from the urines of normal human individuals and leukemic patients

A novel modified nucleoside, 1-α-D-Ribofuranosyl-4-pyridone-3- carboxamide, has been isolated from the urines of one normal human individual and two CML patients. The structure was assigned on the basis of UV, NMR and mass spectral data and confirmed by comparison with an authentic sample synthesized in our laboratory. This constitutes the first example of the occurrence of a nucleoside with an α-riboside linkage in human urine.

Synthesis of methylenebis (Phosphonate) analogues of 2-, 4-, and 6-pyridones of nicotinamide adenine dinucleotide

The synthesis of metabolically stable methylenebis(phosphonate) analogues of 2-, 4-, and 6-pyridones of nicotinamide adenine dinucleotide (NAD) is reported. In contrast to natural pyrophosphates, these NAD analogues are able to penetrate the cell membrane and can be used as probes in cellular assays. Copyright Taylor and Francis Group, LLC.

Monocyclic L-nucleosides, analogs and uses thereof

Novel monocyclic L- nucleoside compounds have general formula (I). Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th 1 and Th 2 response.

Monocyclic L-Nucleosides, analogs and uses thereof

Novel monocyclic L-Nucleoside compounds have the general formula STR1 Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th1 and Th2 response.