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Tyrosyl-alanyl-phenylalanyl-glycinamide, also known as TAFG, is a tetrapeptide consisting of four amino acids: tyrosine, alanine, phenylalanine, and glycine. This specific sequence of amino acids is derived from the larger protein, beta-casomorphin-7, which is a fragment of the casein protein found in milk. TAFG has gained attention for its potential role in modulating the body's response to pain and inflammation, as it is believed to act as an opioid receptor agonist. This means it can bind to opioid receptors in the brain, potentially providing pain relief and other effects similar to those of morphine, but with a different structure and potentially fewer side effects. The study of TAFG and its effects is an area of ongoing research, with implications for the development of new pain management strategies and a deeper understanding of the body's endogenous opioid system.

78700-75-1

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78700-75-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78700-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,0 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 78700-75:
(7*7)+(6*8)+(5*7)+(4*0)+(3*0)+(2*7)+(1*5)=151
151 % 10 = 1
So 78700-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C23H29N5O5/c1-14(27-22(32)18(24)11-16-7-9-17(29)10-8-16)21(31)28-19(23(33)26-13-20(25)30)12-15-5-3-2-4-6-15/h2-10,14,18-19,29H,11-13,24H2,1H3,(H2,25,30)(H,26,33)(H,27,32)(H,28,31)/t14-,18-,19-/m0/s1

78700-75-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-amino-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide

1.2 Other means of identification

Product number -
Other names Tyrosyl-alanyl-phenylalanyl-glycinamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78700-75-1 SDS

78700-75-1Downstream Products

78700-75-1Relevant academic research and scientific papers

Synthesis and pharmacological activity of dermorphin tetrapeptide-analogs

Salvadori,Sarto,Tomatis

, p. 489 - 493 (2007/10/02)

The authors report on the synthesis and pharmacological activity of twenty-four tetrapeptide-analogs of the opioid heptapeptide dermorphin; their terminal amino group were replaced by guanidino functions and/or the C-termini were changed into amide moieti

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