78701-56-1Relevant academic research and scientific papers
SUBSTITUTED P-DIAMINOBENZENE DERIVATIVES
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Page/Page column 97-98, (2010/02/08)
The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
Multi-step process for the production of methanesulfon-m-anisidide, 4'-(9-acridinylamino)-
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, (2008/06/13)
A multi-step method of producing the compound methanesulfon-m-anisidide, 4''-(9-acridinylamino)-, acetate (VII), which may be in free base form and designated NSC 249992, also known as AMSA. This compound is produced by an elegant process from a starting material, 4-butyrylamino-3-methoxy-nitrobenzene, which is later transformed to methanesulfon-m-anisidide, 4''-amino- (IV) and is coupled or joined to 9-chloro-acridine, producing the chloride salt which is later converted to the acetate.
