78749-80-1Relevant academic research and scientific papers
Phenyl urea and phenyl thiourea derivatives as orexin receptor antagonists
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Page/Page column 24-25, (2010/02/05)
The present invention provides phenyl urea and phenyl thiourea derivatives which are non-peptide antagonists of human orexin receptors, in particular orexin-1 receptors, of formula (I) in which: Z represents oxygen or sulfur; and R1to R7represent various substituent groups; and pharmaceutically acceptable salts thereof. In particular, these compounds are of potential use in the treatment of obesity including obesity observed in Type 2(non-insulin-dependent) diabetes patients and/or sleep disorders.
SYNTHESIS AND IR SPECTRA OF SOME 2-AMINOBENZOXAZOLE DERIVATIVES
Simov, D.,Davidkov, K.
, p. 437 - 440 (2007/10/02)
A large number of 5-nitro-, 6-nitro-, 5-chloro-, and 6-bromo-2-aminobenzoxazoles were synthesized by the reaction of benzoxazoline-2-thiones with various amines.It was shown by IR spectroscopy that all of the compounds exist in the amino form in solution,
