78751-61-8

Basic information

• Product Name: 2-(propan-2-yl)pyrene
• Synonyms: 2-Isopropylpyrene; pyrene, 2-(1-methylethyl)-
• CAS NO: 78751-61-8
• Molecular Formula: C₁₉H₁₆
• Molecular Weight: 244.3303
• Mol File: 78751-61-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 396.7°C at 760 mmHg
• Flash Point: 186.7°C
• Density: 1.152g/cm³
• Vapor Pressure: 3.82E-06mmHg at 25°C
• Refractive Index: 1.752
• CAS DataBase Reference: 2-(propan-2-yl)pyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(propan-2-yl)pyrene(78751-61-8)
• EPA Substance Registry System: 2-(propan-2-yl)pyrene(78751-61-8)

Safety Data

• Hazardous Substances Data: 78751-61-8(Hazardous Substances Data)

Upstream product

• 110210-61-2 2-(4,5,9,10-tetrahydropyren-2-yl)-propan-2-ol 
• 129-00-0 pyrene 
• 75-29-6 isopropyl chloride 
• 110210-67-8 2-isopropyl-4,5,9,10-tetrahydropyrene 
• 781-17-9 4,5,9,10-tetrahydropyrene 
• 82799-67-5 2-acetyl-4,5,9,10-tetrahydropyrene 

Relevant articles and documents

Synthesis and structure of 2-substituted pyrene-derived scaffolds

Pyrenes bear a propensity to form fluorescent excimers, and thus this chromophore is often found in sensors and fluorescent probes. 2-Functionalized pyrenes are of particular interest, however the preparation of these scaffolds is not trivial, involving synthetic routes that require 4,5,9,10-tetrahydropyrene as a key intermediate. Herein, the development and optimization of routes for the synthesis of 2-functionalized pyrene-derived building blocks, with potential to be used as tags in the preparation of fluorescent probes, is described. Additionally, the crystal structures of ethyl 4,5,9,10-tetrahydro-2-pyrene-5-oxopentanoate and 2-acetyl-4,5,9,10-tetrahydropyrene revealed distinct conformations of the saturated tetrahydropyrene rings.

Formation of sec-Alkylpyrenes by Friedel-Crafts and Cathodic Alkylation Methods. Structure and Spectroscopic Properties of Products. Catalytic Hydrogenation of Pyrene and Some Alkylpyrenes

Friedel-Crafts isopropylation of pyrene in neat isopropyl chloride yielded a series of mono, di, tri, tetra, and pentaisopropylpyrenes.Tetra and pentacyclopentyl- and cyclohexylpyrenes were formed analogously.Cathodic isopropylation by controlled potential electrolysis yielded both fully aromatic and partly hydrogenated isopropylpyrenes.Structure of these compounds, spectroscopic properties and mechanistic aspects of their formation are discussed.The catalytic hydrogenation (Raney nickel) of pyrene and isopropylpyrenes under very mild conditions has also been studied.