787552-80-1Relevant articles and documents
Synthetic approaches to nuclease-resistant, nonnatural dinucleotides of anti-HIV integrase interest
Chi, Guochen,Nair, Vasu
, p. 1449 - 1468 (2007/10/03)
□ New, nonnatural dinucleotide 5′-monophosphates with a surrogate isonucleoside component of L-related stereochemistry, have been synthesized. Structures of the target compounds were confirmed by multinuclear NMR spectra (1H, 13C, s
Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides
Chi, Guochen,Neamati, Nouri,Nair, Vasu
, p. 4815 - 4817 (2007/10/03)
Remarkable selectivity for inhibition of the strand transfer step of HIV-1 integrase by novel dinucleotides. New, non-natural dinucleotide 5′-monophosphates, with a surrogate isonucleoside component of l-related stereochemistry at the 'terminal' position,