78757-38-7

Basic information

• Product Name: methyl 5-{3,4-bis[(methoxycarbonyl)amino]tetrahydro-2-thienyl}pentanoate
• Synonyms: methyl 5-{3,4-bis[(methoxycarbonyl)amino]tetrahydro-2-thienyl}pentanoate
• CAS NO: 78757-38-7
• Molecular Formula: C14H24N2O6S
• Molecular Weight: 348.41516
• Mol File: 78757-38-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 5-{3,4-bis[(methoxycarbonyl)amino]tetrahydro-2-thienyl}pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-{3,4-bis[(methoxycarbonyl)amino]tetrahydro-2-thienyl}pentanoate(78757-38-7)
• EPA Substance Registry System: methyl 5-{3,4-bis[(methoxycarbonyl)amino]tetrahydro-2-thienyl}pentanoate(78757-38-7)

Safety Data

• Hazardous Substances Data: 78757-38-7(Hazardous Substances Data)

Upstream product

• 68204-53-5 dihydrobromide of cis-3,4-diamino-2-(δ-methoxycarbonylbutyl)thiophane 
• 79-22-1 methyl chloroformate 
• 68204-53-5 dihydrobromide of allo-3,4-diamino-2-(δ-methoxycarbonylbutyl)thiophane 
• 85269-50-7 3-acetylamino-4-benzoylamino-2-(δ-methoxycarbonylbutyl)-2,3-thiophane 
• 608-16-2 (+/-)-biotin methyl ester 

Downstream Products

• 608-16-2 (+/-)-biotin methyl ester 

Relevant articles and documents

SYNTHESIS OF (+-)-BIOTIN FROM A SUBSTITUTED 2,3-DEHYDROTHIOPHANE

(+-)-Biotin has been synthesized from a mixture of cis- and allo-trisubstituted dehydrothiophanes by a scheme providing for the easy elimination of the accompanying allo-substituted thiophane in the form of an intermediate and not as the final isomeric allo-biotin.The imidazoline ring of biotin is formed from a dialkoxycarbonyldiaminothiophane under the conditions of partial hydrolysis of one of the protective groups with the elimination of phosgene from the scheme of synthesis.